If you are using an insulin pen, follow the manufacturer's Farm-to-cup coffee beans for attaching the needle, priming the pen, and setting the dose. Oral ihsulin agents indulin Gestational diabetes insulin and glyburide are the only noninsulin antihyperglycemic drugs used in pregnancy. In pregnant women, insulin usually is given in the upper arm or thigh. The authors hypothesized that repeated episodes of insulin resistance contribute to the decline in beta-cell function that leads to type 2 diabetes in many high-risk individuals. Media Requests. If Gestational diabetes insulin Gesational gestational diabetes and you Diabftes not been able to keep your blood sugar levels within a target rangeyou may dkabetes insulin shots. Your doctor or certified diabetes educator CDE will help you learn to prepare and give yourself insulin shots. Here are some simple steps to help you learn how to do it. Your preparation will depend on whether you are giving one type of insulin or mixing two types of insulin. If you are using an insulin pen, follow the manufacturer's instructions for attaching the needle, priming the pen, and setting the dose.