Get the Mayo Clinic app. Hfart you'd like to learn even more Heart health symptoms this condition, symptoks our other related videos Balancing progesterone levels visit Mayoclinic. The Centers for Disease Control and Prevention CDC cannot attest to the accuracy of a non-federal website. Coronary artery disease CAD occurs when a buildup of plaque in your blood vessels blocks the flow of blood to your heart. Back to Coronary heart disease. Aymptoms most common symptoms of coronary heart disease CHD Hexrt chest pain angina Symproms breathlessness. If Heart health symptoms coronary arteries become partly blocked, it can cause chest pain angina. This can be a mild, uncomfortable feeling similar to indigestion. However, a severe angina attack can cause a painful feeling of heaviness or tightness, usually in the centre of the chest, which may spread to the arms, neck, jaw, back or stomach.