Category: Health

Calcium and bone health

Calcium and bone health

Calcium Calciium sheet for professionals. Calcium and Vitamin D Supplement Safety Fact Sheet Weight control exercises the Healty Latest Callcium Research on Calcium Calcium and bone health Calcjum National Institutes Calciun Health NIH Office of Dietary Supplements ODS. Clinical Trials. No drug references linked in this topic. At birth, the body contains about 26 to 30 g calcium. Additionally, mushrooms, eggs and fortified foods, such as milk and cereals, are good sources of vitamin D. Poor bone health can cause conditions such as rickets and osteoporosis and increase the risk of breaking a bone from a fall later in life. Calcium and bone health

Calcium and bone health -

Whether or not they also interfere with calcium absorption from other calcium-containing foods eaten at the same time seems to be dependent on additional factors. The same is true of 'phytates' in dried beans, cereal husks, and seeds, but to a lesser extent.

People with some degree of lactose maldigestion may avoid dairy products. If you are sensitive to lactose you may not need to eliminate dairy consumption completely: lactose-reduced milks, yogurts with live cultures, and some hard cheeses are normally tolerated.

Another alternative is to take lactase tablets or drops along with dairy foods. If you are lactose intolerant you should consult with your doctor to discuss the best way of ensuring that you get enough calcium, either through diet or if necessary, through supplements. For people who cannot get enough calcium through their diets, supplements may be of benefit.

These should be limited to mg per day or more if advised by a doctor and it is generally recommended that they be taken combined with vitamin D. The two main forms of calcium in supplements are carbonate and citrate.

Calcium carbonate is more commonly available and is absorbed most efficiently when taken with food. Calcium citrate is absorbed equally well when taken with or without food.

Home Patients Prevention Calcium. Social menu Facebook Twitter LinkedIn Instagram YouTube Donate. Prevention Calcium Calcium content of common foods Vitamin D Protein and other nutrients Exercise Falls prevention. Recommendations from the Institute of Medicine of the US are presented in the table below.

Read more about calcium in our Calcium Fact Sheet. Certain compounds in plants e. In addition to spinach, foods with high levels of oxalic acid include collard greens, sweet potatoes, rhubarb, and beans [ 1 ]. The bioavailability of calcium from other plants that do not contain these compounds—including broccoli, kale, and cabbage—is similar to that of milk, although the amount of calcium per serving is much lower [ 3 ].

When people eat many different types of foods, these interactions with oxalic or phytic acid probably have little or no nutritional consequences. Net absorption of dietary calcium is also reduced to a small extent by intakes of caffeine and phosphorus and to a greater extent by low status of vitamin D [ ].

The U. The two most common forms of calcium in supplements are calcium carbonate and calcium citrate [ 1 ]. In people with low levels of stomach acid, the solubility rate of calcium carbonate is lower, which could reduce the absorption of calcium from calcium carbonate supplements unless they are taken with a meal [ 3 ].

Calcium citrate is less dependent on stomach acid for absorption than calcium carbonate, so it can be taken without food [ 1 ]. Other calcium forms in supplements include calcium sulfate, ascorbate, microcrystalline hydroxyapatite, gluconate, lactate, and phosphate [ 14 ].

The forms of calcium in supplements contain varying amounts of elemental calcium. Elemental calcium is listed in the Supplement Facts panel, so consumers do not need to calculate the amount of calcium supplied by various forms of calcium in supplements.

The percentage of calcium absorbed from supplements, as with that from foods, depends not only on the source of calcium but also on the total amount of elemental calcium consumed at one time; as the amount increases, the percentage absorbed decreases.

Absorption from supplements is highest with doses of mg or less [ 15 ]. Some individuals who take calcium supplements might experience gastrointestinal side effects, including gas, bloating, constipation, or a combination of these symptoms.

Calcium carbonate appears to cause more of these side effects than calcium citrate, especially in older adults who have lower levels of stomach acid [ 1 ]. Symptoms can be alleviated by switching to a supplement containing a different form of calcium, taking smaller calcium doses more often during the day, or taking the supplement with meals.

Because of its ability to neutralize stomach acid, calcium carbonate is contained in some over-the-counter antacid products, such as Tums and Rolaids. Depending on its strength, each chewable pill or soft chew provides about to mg of calcium [ 14 ].

A substantial proportion of people in the United States consume less than recommended amounts of calcium. Average daily intakes of calcium from foods and beverages are 1, mg for men age 20 and older and mg for women [ 18 ]. For children age 2—19, mean daily intakes of calcium from foods and beverages range from to 1, mg [ 18 ].

Average daily calcium intakes from both foods and supplements are 1, mg for men, 1, mg for women, and to 1, mg for children [ 18 ]. Poverty is also associated with a higher risk of inadequacy. NHANES data from to show that the risk of inadequate calcium intakes less than to 1, mg is Calcium deficiency can reduce bone strength and lead to osteoporosis, which is characterized by fragile bones and an increased risk of falling [ 1 ].

Calcium deficiency can also cause rickets in children and other bone disorders in adults, although these disorders are more commonly caused by vitamin D deficiency. In children with rickets, the growth cartilage does not mineralize normally, which can lead to irreversible changes in the skeletal structure [ 1 ].

Another effect of chronic calcium deficiency is osteomalacia, or defective bone mineralization and bone softening, which can occur in adults and children [ 1 ].

For rickets and osteomalacia, the requirements for calcium and vitamin D appear to be interrelated in that the lower the serum vitamin D level measured as hydroxyvitamin D [25 OH D] , the more calcium is needed to prevent these diseases [ 21 ].

Hypocalcemia serum calcium level less than 8. Hypocalcemia can be asymptomatic, especially when it is mild or chronic [ 23 ]. When signs and symptoms do occur, they can range widely because low serum calcium levels can affect most organs and symptoms [ 24 ].

The most common symptom is increased neuromuscular irritability, including perioral numbness, tingling in the hands and feet, and muscle spasms [ 23 ].

More severe signs and symptoms can include renal calcification or injury; brain calcification; neurologic symptoms e. Menopause leads to bone loss because decreases in estrogen production reduce calcium absorption and increase urinary calcium loss and calcium resorption from bone [ 1 ].

Over time, these changes lead to decreased bone mass and fragile bones [ 1 ]. The calcium RDA is 1, mg for women older than 50 years vs. People with lactose intolerance, those with an allergy to milk, and those who avoid eating dairy products including vegans have a higher risk of inadequate calcium intakes because dairy products are rich sources of calcium [ 1 , 27 ].

Options for increasing calcium intakes in individuals with lactose intolerance include consuming lactose-free or reduced-lactose dairy products, which contain the same amounts of calcium as regular dairy products [ 1 , 3 ]. Those who avoid dairy products because of allergies or for other reasons can obtain calcium from nondairy sources, such as some vegetables e.

However, these individuals typically need to eat foods fortified with calcium or take supplements to obtain recommended amounts [ 28 ]. This section focuses on six health conditions and diseases in which calcium might play a role: bone health in older adults, cancer, cardiovascular disease CVD , preeclampsia, weight management, and metabolic syndrome.

Bone is constantly being remodeled. Declining levels of estrogen in women during menopause and for approximately 5 years afterward lead to rates of bone resorption that are higher than rates of bone formation, resulting in a rapid decrease in bone mass [ 7 ].

Over time, postmenopausal women can develop osteoporosis, in which bone strength is compromised because of lower BMD and bone quality [ 1 ]. Age-related bone loss can also occur in men and lead to osteoporosis, but fracture risk tends to increase in older men about 5 to 10 years later than in older women [ 1 ].

Osteoporosis increases the risk of fractures, especially of the hip, vertebrae, and forearms [ 1 , 7 ]. FDA has approved a health claim for the use of supplements containing calcium and vitamin D to reduce the risk of osteoporosis [ 29 ]. However, not all research supports this claim.

In spite of the importance of calcium in bone health, observational evidence is mixed on the link between calcium intakes and measures of bone strength in older adults.

Support for such a link comes from an analysis of — NHANES cross-sectional data on 2, adults age 60 and older Results were similar in of the women who were followed for 6 years, even though mean daily intakes of calcium dropped by an average of 40 mg during this period.

Some but not all clinical trials have found that calcium supplementation can improve bone health in older adults. On average, women lost 1. Several recent systematic reviews and meta-analyses have found that supplementation with calcium alone or a combination of calcium and vitamin D increases BMD in older adults.

For example, a systematic review and meta-analysis included 15 RCTs in postmenopausal women but did not include the two studies described in the previous paragraph in 78, women, of which 37, were in the intervention group and 40, were in the control group [ 34 ]. Supplementation with both calcium and vitamin D or consumption of dairy products fortified with both nutrients increased total BMD as well as BMD at the lumbar spine, arms, and femoral neck.

However, in subgroup analyses, calcium had no effect on femoral neck BMD. Earlier systematic reviews and meta-analyses found a positive relationship between calcium and vitamin D supplementation and increased BMD in older males [ 35 ] and between higher calcium intakes from dietary sources or supplements and higher BMD in adults older than 50 [ 25 ].

However, whether these BMD increases were clinically significant is not clear. As with the evidence on the link between increased calcium intakes and reductions in BMD loss, the findings of research on the use of calcium supplementation to prevent fractures in older adults are mixed. For the most part, the observational evidence does not show that increasing calcium intakes reduces the risk of fractures and falls in older adults.

For example, a longitudinal cohort study of 1, women age 42 to 52 years at baseline who were followed for 10—12 years found that fracture risk was not significantly different in calcium supplement users some of whom also took vitamin D supplements and nonusers, even though supplement use was associated with less BMD loss throughout the study period [ 36 ].

Some clinical trial evidence shows that supplements containing a combination of calcium and vitamin D can reduce the risk of fractures in older adults. However, findings were negative in another systematic review and meta-analysis that included 14 RCTs of calcium supplementation and 13 trials comparing calcium and vitamin D supplements with hormone therapy, placebo, or no treatment in participants older than 50 years [ 38 ].

The results showed that calcium supplementation alone had no effect on risk of hip fracture, and supplementation with both calcium and vitamin D had no effect on risk of hip fracture, nonvertebral fracture, vertebral fracture, or total fracture. Similarly, a systematic review of 11 RCTs in 51, adults age 50 and older found that supplementation with vitamin D and calcium for 2 to 7 years had no impact on risk of total fractures or of hip fractures [ 39 ].

Preventive Services Task Force USPSTF concluded with moderate certainty that daily doses of less than 1, mg calcium and less than IU 10 mcg vitamin D do not prevent fractures in postmenopausal women and that the evidence on larger doses of this combination is inadequate to assess the benefits in this population [ 40 ].

The USPSTF also determined the evidence on the benefits of calcium supplementation alone or with vitamin D to be inadequate to assess its effect on preventing fractures in men and premenopausal women. Additional research is needed before conclusions can be drawn about the use of calcium supplements to improve bone health and prevent fractures in older adults.

Calcium might help reduce the risk of cancer, especially in the colon and rectum [ 1 ]. However, evidence on the relationship between calcium intakes from foods or supplements and different forms of cancer is inconsistent [ 4 ]. Most clinical trial evidence does not support a beneficial effect of calcium supplements on cancer incidence.

A 4-year study of 1, mg calcium and 2, IU 50 mcg vitamin D or placebo daily for 4 years in 2, healthy women age 55 years and older showed that supplementation did not reduce the risk of all types of cancer [ 41 ]. The large WHI study described above also found no benefit of supplemental calcium and vitamin D on cancer incidence [ 42 ].

In addition, a meta-analysis of 10 RCTs that included 10, individuals who took supplements containing mg calcium or more without vitamin D for a mean of 3. However, one large clinical trial did find that calcium supplements reduce cancer risk. In this 4-year trial, by the same investigators as the 4-year trial above, 1, women age 55 years or older in Nebraska took 1, to 1, mg calcium alone; 1, to 1, mg calcium plus 1, IU Some scientists have questioned these findings because of the lack of statistical power the studies were designed to detect differences in bone health measures, not cancer incidence , details from the investigators on the study sample, and randomization procedures [ 45 , 46 ].

Observational evidence does not support an association between higher calcium intakes and a lower risk of cancer mortality. An analysis of data on , participants in the Cancer Prevention Study II Nutrition Cohort, who were followed for an average of A systematic review and meta-analysis of 22 observational studies in 2,, participants age 8 and older followed for 4.

Clinical trials have also not shown that supplemental calcium alone or combined with vitamin D has an impact on risk of mortality from all cancers.

Rates of cancer incidence and cancer mortality did not differ between those who did and those who did not receive calcium supplements. In the WHI trial, 36, postmenopausal women were randomly assigned to daily supplementation with a combination of 1, mg calcium and IU 10 mcg vitamin D3 or placebo [ 42 ].

After an average of 7 years, risk of cancer mortality did not differ between groups. The meta-analysis of 10 RCTs that included 10, individuals described above found no impact of calcium supplementation on cancer mortality rates [ 43 ].

A substantial body of evidence has addressed the role of calcium in preventing colorectal cancer or its precursor, adenomas. Much but not all of the observational evidence supports a link between higher calcium intakes and lower risk of colorectal cancer.

A cohort study in 77, adults found that over a mean of 7. Findings were similar for dietary intakes of calcium in two other meta-analyses [ 52 , 53 ]. In spite of the observational evidence supporting an association between higher calcium intakes and lower colorectal cancer risk, clinical trials investigating calcium supplements for prevention of colorectal cancer or adenomas have had mixed results.

A follow-up study by Cauley and colleagues evaluated outcomes 4. Colorectal cancer rates did not differ between groups. Several observational studies have shown that the risk of prostate cancer might be higher with higher calcium intakes, but possibly only when the calcium comes from dairy foods.

In an analysis of data from 2, men who participated in the French SU. MAX Supplementation en Vitamines et Minéraux Antioxydants prospective study and were followed for an average of 7.

The risk was 2. However, in analyses of results for various sources of calcium, only calcium from dairy foods was significantly associated with prostate cancer risk 2. A meta-analysis included 15 epidemiological studies of calcium intake and ovarian cancer risk in , women who developed 7, cases of ovarian cancer [ 59 ].

However, the difference in risk was not statistically significant when both dietary and supplemental calcium intakes were considered.

Bone Cakcium a living tissue, that Wellness programs constantly renewing Calcium and bone health repairing itself from everyday wear and tear. Calcium is essential to Ca,cium the remodeling healty stay balanced. However, like many nutrients, calcium Calcium and bone health absorbed less effectively as we age. Studies of older adults show that adequate calcium intake can slow bone loss and reduce the risk of fracture. Adults between years of age require 1, mg of calcium daily, and those over 50 require 1, mg calcium daily. If you are sensitive to dairy or prefer to avoid it, there are other alternative sources of calcium to choose from. Calcium bbone the key to Nutritional health supplements bone health. These diet tips Calcium and bone health help you eat to Bonr your healtj and boen osteoporosis. Reviewed by Annette Snyder, MS, RD, CSOWM Caldium, a Certified Registered Dietitian at Top Nutrition Hdalth working with clients seeking help for chronic dieting, gut issues, heart health, diabetes and pre-diabetes, and menopause. Calcium is a key nutrient that many of us overlook in our diets. Almost every cell in the body uses calcium in some way, including the nervous system, muscles, and heart. Calcium deficiency can contribute to mood problems such as irritability, anxiety, depression, and difficulty sleeping. Despite these vital functions, many of us are confused about calcium and how to best protect our bones and overall health.

Video

STOP TAKING CALCIUM SUPPLEMENTS! A Critical Look at Current Recommendations for Osteoporosis.

Author: Gutaur

2 thoughts on “Calcium and bone health

Leave a comment

Yours email will be published. Important fields a marked *

Design by ThemesDNA.com